Approximately 43,000 men and women were diagnosed with leukemia in the United States in 2009. The disease is unique in that it is common in both pediatric (<15) cancer patients and in older adult (>60) cancer patients. Of those diagnosed with leukemia, approximately 2600, or six percent, were diagnosed as adolescents or young adults (AYAs). Although there have been vast improvements in survival rates especially for pediatric leukemia, AYAs have not seen these same advancements. AYAs are often caught in the gap between pediatrics and adult cancers and different outcomes were seen in comparing treatments based on pediatric protocols versus adult protocols. Overall, adolescents treated on more aggressive pediatric protocols had improved overall and event-free survival.
Source: Advani A, Hunger S, Burnett A, Acute Leukemia in Adolescents and Young Adults. Semin Oncol. 2009; 36:213-226.
The Dana Farber Consortium Protocol for the Treatment of Adolescents and Young Adults With Acute Lymphoblastic Leukemia: A Single Institution Experience in Saudi Arabia.
Clin Lymphoma Myeloma Leuk. 2017 Feb 16;:
Authors: Alabdulwahab AS, Elsayed HG, Sherisher MA, Elbjeirami...
Acute lymphoblastic leukemia in adolescents and young adults.
Cancer. 2017 Mar 22;:
Authors: Rytting ME, Jabbour EJ, O'Brien SM, Kantarjian HM
Acute lymphoblastic leukemia (ALL) in the adolescent and young adult (AYA) population is a difficult clinical problem. The AYA...
Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature.
Case Rep Oncol Med. 2017;2017:2832180
Authors: Khan M, Korphaisarn K, Saif A, Foo WC, Kopetz S
Safety, efficacy, and clinical utility of asparaginase in the treatment of adult patients with acute lymphoblastic leukemia.
Onco Targets Ther. 2017;10:1413-1422
Authors: Koprivnikar J, McCloskey J, Faderl S
Adults with acute lymphoblastic leukemia...
Adolescent and young adult oncology patients: Disparities in access to specialized cancer centers.
Cancer. 2017 Feb 27;:
Authors: Alvarez E, Keegan T, Johnston EE, Haile R, Sanders L, Saynina O, Chamberlain LJ
BACKGROUND: Adolescents and young adults (AYAs) ages 15 to...
Small Numbers, Big Challenges: Adolescent and Young Adult Cancer Incidence and Survival in New Zealand.
J Adolesc Young Adult Oncol. 2017 Feb 16;:
Authors: Ballantine KR, Watson H, Macfarlane S, Winstanley M, Corbett RP, Spearing R, Stevanovic V, Yi M, Sullivan MJ
PURPOSE: This study was undertaken to determine cancer...
Adolescents and Young Adults with Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia: Impact of Care at Specialized Cancer Centers on Survival Outcome.
Cancer Epidemiol Biomarkers Prev. 2017 Mar;26(3):312-320
Authors: Wolfson J, Sun CL, Wyatt L, Stock W, Bhatia S...
[Characteristics of Adolescent and Young Adult Cancer].
Gan To Kagaku Ryoho. 2017 Jan;44(1):7-11
Authors: Horibe K
In adolescent and young adult(AYA)population, cancer is the leading cause of death due to illness with...
A review of the management of adults with T-cell acute lymphoblastic leukemia.
Blood. 2017 Jan 23;:
Authors: Marks DI, Rowntree C
T-cell acute lymphoblastic leukemia (ALL) is a rare disease in adults with inferior survival outcomes compared to those seen in pediatric patients. Although potentially curable with about 50...
The positive effect of a dedicated adolescent and young adult fertility program on the rates of documentation of therapy-associated infertility risk and fertility preservation options.
Support Care Cancer. 2017 Feb 02;:
Authors: Lewin J, Ma JM, Mitchell L, Tam S, Puri N, Stephens D, Srikanthan A,...
Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010.
Neuro Oncol. 2016 Dec 29;:
Authors: Zhang AS, Ostrom QT, Kruchko C, Rogers L, Peereboom DM, Barnholtz-Sloan JS
The Benefits and Burdens of Cancer: A Prospective Longitudinal Cohort Study of Adolescents and Young Adults.
J Palliat Med. 2017 Jan 04;:
Authors: Straehla JP, Barton KS, Yi-Frazier JP, Wharton C, Baker KS, Bona K, Wolfe J, Rosenberg AR
BACKGROUND: Adolescents and early young adults (AYAs) with cancer are at high risk...
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